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CBC, LFT & RFT Interpretation – A quick review 🩸 COMPLETE BLOOD COUNT (CBC) 🔹 RBC / Hb / HCT → Oxygen carriers ↑ Dehydration, Polycythemia ↓ Anemia, Chronic illness 🔹 WBC → Body’s defense army ↑ Infections, Inflammation ↓ Immune suppression, Viral disease 🔹 Neutrophils → First responders ↑ Bacterial infection, Leukemia ↓ Adaptive immunity shift 🔹 Platelets → Clotting & repair ↑ Inflammation, Neoplasia ↓ Corticosteroid therapy 🧪 LIVER FUNCTION TESTS (LFT) 🔹 ALT / AST → Hepatocellular injury (Hepatitis, toxins, muscle injury) 🔹 ALP → Cholestasis, bile duct epithelium, steroid effect 🔹 GGT → Biliary hyperplasia, parasitic/allergic conditions 🔹 Bilirubin → RBC breakdown, jaundice, bile duct obstruction 🩺 RENAL FUNCTION TESTS (RFT) 🔹 BUN → Protein metabolism ↑ Azotemia, dehydration ↓ Liver disease, malnutrition 🔹 Creatinine → Kidney filtration marker (GFR) ↑ Reduced kidney function 🔹 SDMA → Early CKD biomarker – rises before creatinine ✅ These panels together give a 360° view of systemic health, helping in diagnosis, prognosis, and monitoring
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Among different classes of GSTs, role of Lambda class GSTs has been reported in As stress response ( Glutathione S-Transferase The GSTs are a super family of enzymes that are notable for their role in phase II detoxification reactions
