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α-Tocopherol is uniquely suited to intercept peroxyl radicals and thus prevent a chain reaction of lipid peroxidation ( Figure 2 )

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The inhibitory action of IL-6 is prevented by the addition of N-acetyl-cysteine (NAC), an antioxidant that restores intracellular GSH concentrations, suggesting the involvement of prooxidant substances in IL-6-induced effects