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They reported that at low concentrations (0.9–2.5 mg/m 3 ) formaldehyde is likely to react with the extracellular components of the cells at or near the cell membrane, while at higher doses (7.5–18.5 mg/m 3 ) responses are observed in both extracellular and intracellular sites involving more genes in the response

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Most evidence so far originates from preclinical models demonstrating accelerated tissue regeneration