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218 Another study that analyzed data from 10,480 NHANES (2005–2016) participants found those with the highest folate combined with the lowest B 2 intake had the highest rate of death from cardiovascular disease during an average of 8.5 years of monitoring

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You experience persistent symptoms: If you are dealing with chronic fatigue, unexplained brain fog, or digestive distress, it is vital to rule out underlying medical issues with a nurse practitioner or doctor before trying to "fix" it with supplements alone