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Evidence base for dosing: Primarily animal infusion studies and in‑vitro concentration work (no standardized, FDA‑recognized human protocol) Core research theme: Anabolism / nitrogen retention, growth signaling, tissue‑response modeling Dosing & Reconstitution Standard Approach (Preclinical context) Standard Approach Important reality: For des(1‑3) IGF‑1, the clearest dosing in the peer‑reviewed record is from animal studies, commonly delivered via continuous infusion (osmotic minipump) rather than intermittent injections

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10.1038/s41467-018-08247-x Nat