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The combination of hormone optimization, peptides, and metabolic support has been transformative—not just for my weight, but for my entire quality of life.” — Lisa M., 46, Nonprofit Executive Director, Old Town Key Takeaways: Your Perimenopause Weight Gain Action Plan If you take nothing else from this article, remember these critical points: Perimenopause fundamentally changes your metabolism—it’s not about willpower: Hormone fluctuations affect insulin sensitivity, muscle mass, fat distribution, sleep, and stress response