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In the case of the subject that dropped out of the study, the pre-treatment laboratory work shows a baseline depletion of the glutathione reserve, high levels of superoxide dismutase despite normal glutathione peroxidase, and elevated lipid peroxides

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The body needs time to adapt to each dose level, and GI side effects (nausea, decreased appetite, occasional diarrhea) tend to peak within the first 1-2 weeks of a new dose and then diminish