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Specifically, PPARα activation reduces LPS-induced IL-1β production (Subramaniam and Federoff, 2017), whereas rosiglitazone-mediated PPARγ activation decreases TNF-α secretion (Pisanu et al., 2014)

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Amylin delivered into the ventral tegmental area reduced food-evoked dopamine release in the medial prefrontal cortex and reduced impulsive food-directed responding in rats