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In addition, metal ions such as Al 3+ , Zn 2+ , Cu 2+ and Fe 2+ readily produced free radicals that translated into induction of lipid peroxidation, mitochondrial oxidation etc, thus underlining the potential therapeutic effect of metal chelators such as curcumin [277-284]

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24 weeks 2 x 5 mg or 1 x 10 mg Doses are still well under 2 mg/week

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