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6.2 Concluding remarks and future directions In conclusion, this review has systematically traced SFN’s journey from its biosynthetic origins in plants to its multifaceted mechanisms of action in human cancer prevention and therapy, ultimately addressing the translational challenges that currently limit its clinical application

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Assembly of the Bak apoptotic pore: A critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis

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