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Proteomic platforms have additionally expanded the list of candidate serum biomarkers, identifying elevations in immune-modulatory proteins such as AXIN1, STAMBP, SIRT2, and additional chemokines and signaling molecules (CCL2, CCL17, CXCL9, and CXCL11), which are associated with symptom severity and disease burden [22,51]

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This iron-overloaded and pro-oxidative milieu creates conditions conducive to ferroptosis in ectopic endometrial tissue in endometriosis